Age: 40
Occupation: Actor
Previous TIME 100 Appearances: 0
He was 2009's breakout awkward funny guy, going from relative obscurity to show-stealing fame with his role in The Hangover, in which he played a shaggy-faced dimwit who accessorized with a stolen baby and a man-purse. Fans discovered a treasure-trove of viral Galifianakis skits online several pairing the actor with two snarky ferns and by year's end, he was featured prominently in the ads for Up in the Air, despite the fact that his cameo lasted only a few seconds.